Table 1

 Clinical and laboratory changes from baseline in patients with or without anti-CCP antibodies after 6 months’ MTX treatment

Change from baselineAnti-CCP positive (n = 14)Anti-CCP negative (n = 6)
None of the differences were significant.
ACR <20%, No (%)3 (21)1 (17)
ACR 20%, No (%)9 (64)2 (33)
ACR 50%, No (%)1 (7)1 (17)
ACR 70%, No (%)1 (7)2 (33)
CRP (mg/l)0 (0–6)15 (0–24)
ESR (mm/1st h)16 (7–30)23 (4–25)
IgM RF (BI)0.7 (0.4–1.7)0.3 (0–1.8)