Table 2

 Immunohistochemical findings related to macrophage functions in patients with WG

SampleCD68MARCO*MMP-1†MMP-9‡ADAM9§ADAM12¶SGP28vWFMCT
*Macrophage scavenger receptor; †collagenase-1; ‡gelatinase-B; §meltrin-γ; ¶meltrin-α.
Mucosa  =  nasopharyngeal mucosa.
Score value: –  =  no immunoreactivity; ±  =  only a few immunoreactive profiles; +  =  some immunoreactive profiles; ++  =  many immunoreactive profiles.
Patient group
1, lung++±++++++++++
2, lung++±++++++
3, lung++±++++++++++
4, skin++±++++++
5, skin++±++++++++++
6, skin±++++++
7, mucosa++±+++++++++