BILAG renal score
BILAG, British Isles Lupus Assessment Group; HPF, high power field; rbc, red blood cell; wc, white cell. |
CATEGORY A |
Disease thought to be sufficiently active to require disease modifying treatment, prednisolone >20 mg/dl or immunosuppressant. |
Two or more of the following present, providing (1), (4), or (5) is included: |
(1) Proteinuria, defined as |
Urinary dipstick increased by two or more levels; or |
24 hour urinary protein rising from <0.20 g to >1 g; or |
24 hour urinary protein rising from >1 g by 100%; or |
Newly documented proteinuria of >1 g |
(2) Accelerated hypertension |
(3) Deteriorating renal function, defined as |
Plasma creatinine >130 μm/l and having risen to >130% of previous value; or |
Creatinine clearance having fallen to <67% of previous value; or |
Creatinine clearance <50 ml/min and previously >50 ml/min or not measured. |
(4) Active urinary sediment (on uncentrifuged specimen): pyuria (>5 wc/hpf), haematuria (>5 rbc/hpf), or red cell casts in the absence of infection or other cause |
(5) Histological evidence of active nephritis by WHO criteria within last 3 months (or since previous assessment if seen less than 3 months ago; sclerosis without inflammation not counted) |
CATEGORY B |
Disease requiring only symptomatic treatment. |
One of the following present: |
(1) One of the category A criteria |
(2) Proteinuria |
Urinary dipstick which has risen by 1+or more to at least 2+; or |
24 hour urinary protein rising from >1 g by >50% but <100% |
(3) Raised plasma creatinine: Plasma creatinine >130 μm/l and having risen to 115% of previous value |
CATEGORY C |
Stable, mild disease |
One of the following present: |
(1) 24 hour urinary protein >0.25 g |
(2) Urinary dipstick 1+ or more |
(3) Rising blood pressure, defined as systolic rise of ⩾30 mm Hg and diastolic rise of ⩾15 mm Hg (provided the recorded values are >140/90 mm Hg) |
CATEGORY D |
Previous renal disease |
CATEGORY E |
No previous renal disease |