Table 1

 Characteristics of ACPA positive patients with SLE

Patient NoRFAnti-CCPAnti-PepAAnti-PepBFine antinuclear reactivitiesSERxRA critClinical signs
RF titres and anti-CCP2 concentrations (U/ml, cut off point 42 U/ml) are given. Anti-pepA and anti-pepB antibodies were scored −,1+, 2+, or 3+. Fine antinuclear reactivities are noted. Shared epitope (SE) status is recorded as the presence of 0, 1, or 2 copies (0, 1, 2). Radiographic data (Rx) are listed as the presence (+) or absence (−) of erosions. ACR classification criteria for RA (RA crit) were noted as fulfilled (+) or not (−). Clinical symptoms being part of the ACR criteria for SLE are listed. NA =  not available.
112801863+3+SSB, Ro600Arthritis, proteinuria, leucopenia, lymphopenia
264091+RNP-C0+Butterfly rash, photosensitivity, arthritis, lymphopenia
30168dsDNANANANAButterfly rash, oral ulcers, arthritis, proteinuria, cellular casts
4083SmB, dsDNANANANAButterfly rash, photosensitivity, oral ulcers, arthritis, pleuritis, leucopenia
58021+Histones, dsDNANANANAButterfly rash, arthritis, proteinuria, cellular casts
6076SmB, RNP-A, RNP-C, ribosomal P, histones1NA+Arthritis, pericarditis, pleuritis, proteinuria, thrombopenia, leucopenia, haemolytic anaemia
74064SmD, SmB, RNP-C, RNP-70k, ribosomal P1NAButterfly rash, photosensitivity, pleuritis, arthritis, leucopenia
8058Negative0NAButterfly rash, photosensitivity, lymphopenia, leucopenia
9320110SmB, RNP-70k, RNP-A, RNP-C, histones, dsDNA0+Arthritis, leucopenia
10320781+1+SmB, RNP-70k, RNP-A, RNP-C0++Arthritis, pleuritis, lymphopenia
118056RNP-A, histones, ribosomal P1Butterfly rash, photosensitivity, lymphopenia, leucopenia
1264052RNP-70k, RNP-A0++Butterfly rash, oral ulcers, arthritis, cellular casts, proteinuria, lymphopenia, leucopenia
13320>16002+2+Ro600++Butterfly rash, arthritis, lymphopenia