Table 2

 Outcomes of treatment groups during the 12 months study

PlaceboCiclosporin
Baseline48 weeksBaseline48 weeks
*p<0.05, **p<0.001—significant differences from baseline; †p<0.05—significant between-group differences.
TJI, mean (SD)44.3 (38.2)27.4 (27)**35.4 (34.8)23.4 (37)**
TJC, mean (SD)28.3 (19.2)19.7 (17.9)**22.6 (15.9)15. 3 (16.5)**
SJC, mean (SD)11.7 (8.6)7.9 (5)11.7 (9.7)6.7 (6.5)**
ESR (mm/1st h), mean (SD)24.5 (19.3)22.9 (14.9)24.6 (21.6)25.5 (17.3)
CRP (mg/l), mean (SD)15.4 (13.3)12.6 (9)17.4 (14.5)12.7 (14.3)*
PASI, mean (SD)2.2 (2.7)1.9 (2.8)2 (2.3)0.8 (1.3)**†
Patient global pain (VAS/cm), mean (SD)5.1 (2.3)4.9 (2.9)4.7 (2.2)3.9 (2.4)
Patient global disease activity (VAS/cm), mean (SD)5.4 (2.2)4.9 (2.8)5.1 (2.3)4.1 (2.7)
HAQ, mean (SD)1.1 (0.45)0.9 (0.52)1.0 (0.62)0.9 (0.61)