Changes in study variables during follow up
| Variable | Month | Cy | MP | p Value (Friedman’s) |
|---|---|---|---|---|
| Values are expressed as median (minimum–maximum). | ||||
| *Significant. | ||||
| Leucocytes (cells ×106/l) | 1 | 6.11(4–7.6) | 9.6 (9–10.3) | |
| 6 | 6.4 (5.9–7) | 6.4 (5.5–7.3) | ||
| 12 | 6.2 (4.3–69) | 5.1 (4.3–6) | 0.745 | |
| Lymphocytes (cells ×106/l) | 1 | 1.4 (0.67–1.4) | 1.2 (0.75–1.7) | |
| 6 | 1.4 (0.67–1.6) | 1.4 (0.9–1.2) | ||
| 12 | 12.2 (11.8–14.9) | 12.1 (11–15.3) | 0.670 | |
| SLEDAI | 1 | 10 (8–23) | 14 (7–23) | |
| 6 | 2 (0–8) | 5 (1–8) | ||
| 12 | 1 (0–5) | 4 (0–30) | 0.007* | |
| SLICC | 1 | 0.88 (0–2) | 0.82 (0–1) | |
| 6 | 0.79 (0–1) | 0.81 (0–1) | ||
| 12 | 0.72 (0–1) | 0.80 (0–1) | 0.071 | |
| Prednisone (mg/day) | 1 | 60 (30–60) | 45 (20–60) | |
| 6 | 15 (10–35) | 27.5 (5–45) | 0.001* | |
| 15 (10–35) | 11.2 (5–20) | 15.6 (5–30) | 0.04* | |