Binding of peptides to human sera in ELISA
Peptides | Controls | Controls over mean ±2SD | Patients with RA over mean ±2SD |
---|---|---|---|
Mean (SD) absorbance | (n) | (n) | |
NS, not significant, **p<0.01 and ***p<0.001 compared with controls. | |||
C-telopeptide of α1(I) | |||
Arginine peptide | 0.288 (0.142) | 4/81 | 6/120NS |
Citrulline peptide | 0.314 (0.117) | 2/81 | 24/120*** |
C-telopeptide of α2(I) | |||
Arginine peptide | 0.692 (0.326) | 3/81 | 22/120*** |
Citrulline peptide | 0.763 (0.356) | 3/81 | 12/120** |
CC1 = C-telopeptide of α1(II) | |||
Arginine peptide | 0.181 (0.077) | 2/81 | 54/120*** |
Citrulline peptide | 0.155 (0.065) | 2/81 | 35/120*** |
CC2 | |||
Arginine peptide | 0.162 (0.053) | 3/81 | 50/120*** |
Citrulline peptide | 0.135 (0.054) | 1/81 | 25/120*** |
CC3 | |||
Arginine peptide | 0.182 (0.0073) | 2/81 | 63/120*** |
Citrulline peptide | 0.181 (0.067) | 2/81 | 32/120*** |
CC4 | |||
Arginine peptide | 0.179 (0.070) | 3/81 | 60/120*** |
Citrulline peptide | 0.184 (0.071) | 2/81 | 22/120*** |