Minimal clinically important improvement (MCII) scores according to patients’ location of OA
| Patient reported outcomes | Knee OA | Hip OA | ||||||
|---|---|---|---|---|---|---|---|---|
| Absolute change | Relative change | Absolute change | Relative change | |||||
| MCII | (95% CI) | MCII (%) | (95% CI) | MCII | (95% CI) | MCII (%) | (95% CI) | |
| The MCII was defined as the 75th centile of the change in score among patients whose evaluation of response to treatment was “good”, for the three patient reported outcomes: pain, as assessed on a visual analogue scale (VAS); global assessment of disease status, on a VAS; or the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) function subscale score. | ||||||||
| Pain (0–100 mm VAS), mm | −19.9 | (−21.6 to −17.9) | −40.8 | (−44.8 to −36.1) | −15.3 | (−17.8 to −12.5) | −32.0 | (−38.5 to −24.0) |
| Patient global assessment (0–100 mm VAS), mm | −18.3 | (−19.8 to −16.7) | −39.0 | (−45.8 to −30.6) | −15.2 | (−16.9 to −13.4) | −32.6 | (−38.7 to −25.2) |
| WOMAC function score (0–100) | −9.1 | (−10.5 to −7.5) | −26.0 | (−28.6 to −23.3) | −7.9 | (−8.8 to −5.0) | −21.1 | (−24.8 to −17.0) |