Table 2

Histological features of CNO lesions

CNO subset	Patient	Time between first symptom and diagnosis	Bone lesions	Bones affected	Cellular predominance in bone lesions		Hyperostosis	Fibrosis of the marrow space
CNO subset	Patient	(months)	(n)	(n)	Monocytes/lymphocytes	Granulocytes	Hyperostosis	Fibrosis of the marrow space
ND, not done.
Diagnosis was confirmed by biopsy in all patients except Nos 11, 12, 29, 14, and 26.
Unifocal non-recurrent
	6	26	1	1	++	−	+	+
	11	4	1	1	ND	ND	ND	ND
	12	18	1	1	ND	ND	ND	ND
	19	4	1	1	+	−	(+)	+
	21	12	1	1	+	−	+	+
	24	1	1	1	+	−	−	−
	28	1	1	1	+	−	−	(+)
	29	9	1	1	ND	ND	ND	ND
	30	12	1	1	+	−	−	−

Unifocal recurrent
	10	3	1	1	+	−	−	+
	27	1	1	1	++	−	+	−
	16	11	1	1	+	−	+	+

Multifocal non-recurrent
	1	1	2	2	+	(+)	(+)	+
	4	2	2	2	+	−	−	+
	14	18	2	2	ND	ND	ND	ND
	20	9	2	2	+	−	++	+
	23	7	2	2	+	+	+	+
	15	36	3	3	++	−	+	−
	2	1	4	4	+	−	+	+
	22	12	5	5	+	(+)	−	+
	26	1	6	2	ND	ND	ND	ND

Multifocal recurrent (CRMO)
	8	12	2	2	++	−	+	−
	17	2	2	2	++	(+)	+	+
	3	13	2	2	+	+	+	+
	5	4	3	3	(+)	+	+	+
	9	20	3	3	(+)	(+)	+	+
	7	26	3	3	(+)	+	+	+
	13	3	3	3	+	++	+	−
	18	2	3	3	+	+	+	+
	25	1	2	2	+	+	+	+