Demographic and clinical characteristics of patients with SSc and controls*
| SSc (n = 43) | Limited SSc (n = 32) | Diffuse SSc (n = 11) | lSSc v dSSc (p value) | |
|---|---|---|---|---|
| *Healthy controls comprised 35 subjects (seven male, 28 female) aged 59 years (range 31–75). | ||||
| For definitions, see text. M, male; F, female; ANA, antinuclear antibodies; Scl-70, anti-Scl-70 autoantibodies; ACA, anticentromere antibodies; Tlco, carbon monoxide transfer factor. | ||||
| Age (years) | 61 (24–79) | 63 (43–79) | 55 (24–79) | 0.13 (NS) |
| Disease subset | 32 | 11 | ||
| Sex | ||||
| M | 6 | 3 | 3 | |
| F | 37 | 29 | 8 | |
| Disease duration | 5 (2–36) | 5 (1–30) | 5 (1–22) | 0.72 (NS) |
| Telangiectasias | ||||
| + | 26 | 18 | 7 | |
| − | 17 | 14 | 4 | |
| Fingertip ulcers | ||||
| + | 16 | 10 | 7 | |
| − | 27 | 22 | 4 | |
| Other skin ulcers | ||||
| + | 11 | 6 | 5 | |
| − | 32 | 26 | 6 | |
| Skin score | 10 (3–41) | 8.5 (3–30) | 21.50 (16–41) | <0.001 |
| Capillaroscopy | ||||
| Early | 5 | 5 | 0 | |
| Active | 31 | 25 | 6 | |
| Late | 7 | 2 | 5 | |
| Autoantibodies | ||||
| ANA+ | 39 | 28 | 11 | |
| Scl-70+ | 8 | 2 | 6 | |
| ACA+ | 16 | 16 | 0 | |
| ANA− | 4 | 4 | 0 | |
| Tlco (%) | 69 (26–144) | 75 (35–144) | 54 (26–102) | 0.003 |