Clinical and laboratory features of patients with CNO
| CNO subset | Patient | Sex | Age | Bone lesions (n) | Joints affected by arthritis | Pustulosis | HLA-B27 | ANA | Leucocytes/l (×109) | ESR (mm/1st h) | CRP (mg/l) | Ferritin (μg/l) | No of relapses |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SC, sternoclavicular joint; ND, not done; Neg, negative; Pos, positive; CNO, chronic non-bacterial osteomyelitis; CRMO, chronic recurrent multifocal osteomyelitis. | |||||||||||||
| Age is given in years and months. | |||||||||||||
| Unifocal non-recurrent | |||||||||||||
| 6 | M | 8 y 10 m | 1 | Hip right | No | Neg | Neg | 5.2 | 6 | 0 | 28 | 0 | |
| 11 | F | 9 y 7 m | 1 | No | No | ND | Neg | 7.0 | 3 | 0 | 15 | 0 | |
| 12 | M | 16 y 4 m | 1 | Ankle left | No | Neg | Neg | 8.5 | 17 | 13 | ND | 0 | |
| 19 | F | 15 y 4 m | 1 | Sacroiliac joint right | Yes | Neg | Neg | 4.4 | 8 | 0 | 18 | 0 | |
| 21 | M | 14 y 11 m | 1 | Shoulder left | No | Pos | Neg | 6.7 | 8 | 0 | 14 | 0 | |
| 24 | F | 10 y 11 m | 1 | No | No | ND | ND | 12.9 | 24 | 0 | ND | 0 | |
| 28 | F | 1 y 9 m | 1 | No | No | ND | ND | 13.5 | 22 | 0 | ND | 0 | |
| 29 | F | 9 y 11 m | 1 | Ankle left | No | Neg | ND | 8.7 | 10 | 0 | ND | 0 | |
| 30 | F | 13 y | 1 | Knee right | No | Neg | ND | 7.0 | 5 | 0 | 51 | 0 | |
| Unifocal recurrent | |||||||||||||
| 10 | F | 3 y 10 m | 1 | No | No | Pos | Neg | 11.2 | 12 | 0 | 40 | 1 | |
| 27 | F | 10 y 5 m | 1 | No | No | Neg | 1:80 | 7.7 | 30 | 17 | ND | 2 | |
| 16 | F | 11 y 2 m | 1 | SC left | No | Neg | Neg | 5.1 | 4 | 0 | 15 | 7 | |
| Multifocal non-recurrent | |||||||||||||
| 1 | F | 11 y 6 m | 2 | Symphysis | Yes | ND | Neg | 7.0 | 38 | 0 | 20 | 0 | |
| 4 | F | 9 y | 2 | SC right | No | Pos | Neg | 10.7 | 33 | 7 | 62 | 0 | |
| 14 | F | 10 y 11 m | 2 | Both SC | Yes | Neg | Neg | 5.6 | 5 | 0 | 54 | 0 | |
| 20 | F | 11 y 9 m | 2 | Hip right | No | Neg | Neg | 6.6 | 8 | 0 | 47 | 0 | |
| 23 | M | 10 y 11 m | 2 | SC left | No | Pos | Neg | 9.0 | 24 | 0 | 48 | 0 | |
| 15 | F | 21 y 3 m | 3 | Left metatarsal + ankle | No | Pos | ND | 6.7 | 5 | 0 | 32 | 0 | |
| 2 | M | 7 y 8 m | 4 | Ankle left, SC left | Yes | ND | Neg | 9.1 | 10 | 0 | ND | 0 | |
| 22 | F | 14 y 3 m | 5 | Both SC, hip right | No | ND | Neg | 8.6 | 21 | 0 | ND | 0 | |
| 26 | M | 8 y 11 m | 6 | No | No | Neg | 1:80 | 8.5 | 3 | 12 | 53 | 0 | |
| Multifocal recurrent (CRMO) | |||||||||||||
| 8 | M | 6 y 5 m | 2 | Knee right | No | Neg | Neg | 7.8 | 15 | 0 | ND | 1 | |
| 17 | F | 9 y 8 m | 2 | SC left, shoulder left | No | Neg | 1:80 | 7.7 | 25 | 85 | 38 | 1 | |
| 3 | F | 13 y 1 m | 2 | SC left, ankle right | No | Neg | Neg | 13.6 | 18 | 0 | 29 | 8 | |
| 5 | F | 11 y 10 m | 3 | SC left, ankle right | Yes | Neg | ND | 12.8 | 43 | 0 | 245 | 1 | |
| 9 | F | 11 y 2 m | 3 | Both knees, ankle left | No | Neg | Neg | 10.8 | 20 | 29 | 16 | 2 | |
| 7 | M | 6 y 10 m | 3 | Ankle left, SC left | No | Neg | ND | 8.2 | 7 | 0 | ND | 3 | |
| 13 | F | 11 y 10 m | 3 | Both SC | No | Neg | Neg | 7.9 | 15 | 0 | 37 | 4 | |
| 18 | F | 15 y 5 m | 3 | Hip left, SC left | Yes | Neg | Neg | 8.4 | 6 | 15 | ND | 4 | |
| 25 | M | 12 y 5 m | 2 | Temporomandib. joint | Yes | Neg | Neg | 9.0 | 32 | 12 | 25 | 10 | |