Correlation coefficients, significance, and number of observations of the variables analysed
Larsen score | Larsen score | ESR | CRP | COMP | RF IgG | RF IgA | RF IgM | Anti-CCP | Anti-IL1α | Epitope single dose | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|
year 5 | year 10 | year 0 | year 0 | year 0 | year 0 | year 0 | year 0 | year 0 | year 0 | |||
*Correlation significant at the 0.05 level; **correlation significant at the 0.01 level; ***correlation significant at the 0.001 level (all two tailed). | ||||||||||||
Anti-CCP, antibodies against cyclic citrullinated peptide; anti-IL1α, antibodies against interleukin 1α; COMP, cartilage oligomeric matrix protein; CRP, C reactive protein; ESR, erythrocyte sedimentation rate; n, number of patients; PC, Pearson correlation; RF, rheumatoid factor. | ||||||||||||
Larsen score (year 10) | (PC) | 0.848*** | ||||||||||
(n) | 129 | |||||||||||
ESR year 0 | (PC) | 0.436*** | 0.397*** | |||||||||
(n) | 139 | 155 | ||||||||||
CRP Year 0 | (PC) | 0.403*** | 0.391*** | 0.737*** | ||||||||
(n) | 116 | 128 | 147 | |||||||||
COMP year 0 | (PC) | 0.198* | 0.133 | 0.228** | 0.221** | |||||||
(n) | 133 | 150 | 169 | 142 | ||||||||
IgG RF year 0 | (PC) | 0.233** | 0.205* | 0.124 | 0.036 | −0.105 | ||||||
(n) | 136 | 152 | 174 | 143 | 166 | |||||||
IgA RF year 0 | (PC) | 0.392*** | 0.363*** | 0.137 | 0.047 | −0.106 | 0.593*** | |||||
(n) | 136 | 152 | 174 | 143 | 166 | 176 | ||||||
IgM RF year 0 | (PC) | 0.233** | 0.248** | 0.129 | 0.164 | −0.133 | 0.579*** | 0.610*** | ||||
(n) | 136 | 152 | 174 | 143 | 166 | 176 | 176 | |||||
Anti-CCP year 0 | (PC) | 0.344*** | 0.420*** | 0.128 | 0.131 | −0.117 | 0.296*** | 0.556*** | 0.464*** | |||
(n) | 136 | 152 | 174 | 143 | 166 | 176 | 176 | 176 | ||||
Anti-IL1α year 0 | (PC) | −0.111 | −0.092 | 0.004 | −0.016 | 0.055 | 0–.103 | 0.021 | −0.086 | |||
(n) | 141 | 157 | 181 | 148 | 171 | 176 | 176 | 176 | ||||
Single dose shared epitope | (PC) | 0.108 | 0.114 | 0.074 | 0.095 | −0.093 | 0.018 | 0.145 | 0.186* | 0.263** | −0.080 | |
(n) | 137 | 154 | 169 | 139 | 162 | 165 | 165 | 165 | 165 | 171 | ||
Double dose shared epitope | (PC) | 0.145 | 0.115 | 0.040 | 0.171* | 0.033 | 0.066 | 0.126 | 0.095 | 0.191* | −0.103 | 0.288** |
(n) | 138 | 155 | 171 | 141 | 164 | 167 | 167 | 167 | 167 | 173 | 171 |