Sociodemographic and health related characteristics of patients with gout and osteoarthritis: the UK General Practice Research Database (GPRD), 1990–99
| Patients’ characteristic/disease related factor | Patients with gout (n = 56 483) | Patients with OA (n = 150 867) | Crude OR (gout vOA) | 95% CI | Adjusted† OR (gout v OA) | 95% CI |
|---|---|---|---|---|---|---|
| *p<0.001 for difference; †adjusted for age and sex. | ||||||
| Results are shown as No (%) unless otherwise indicated. | ||||||
| Sociodemographic | ||||||
| Age (years), mean (SD)* | 60.5 (15.4) | 66.8 (13.4) | –– | –– | ||
| Sex (male) | 44959 (79.6) | 51019 (33.8) | 7.64 | 7.46 to 7.81 | –– | –– |
| Comorbidity | ||||||
| Coronary artery disease | 14039 (24.9) | 29855 (19.8) | 1.34 | 1.31 to 1.37 | 1.75 | 1.70 to 1.79 |
| Hypertension | 13483 (23.9) | 30714 (20.4) | 1.23 | 1.20 to 1.26 | 1.52 | 1.48 to 1.56 |
| Diabetes mellitus | 3632 (6.4) | 8995 (6.0) | 1.08 | 1.04 to 1.13 | 1.11 | 1.06 to 1.16 |
| Nephrolithiasis | 506 (0.9) | 996 (0.7) | 1.36 | 1.22 to 1.52 | 0.87 | 0.77 to 0.97 |
| Chronic renal failure | 565 (1.0) | 365 (0.2) | 4.17 | 3.65 to 4.75 | 4.95 | 4.28 to 5.72 |
| Renal transplant | 103 (0.2) | 11 (0.0) | 25.05 | 13.45 to 46.66 | 25.13 | 12.97 to 48.68 |
| Concomitant drug use | ||||||
| Diuretics | 18392 (32.6) | 51366 (34.0) | 0.94 | 0.92 to 0.96 | 1.72 | 1.67 to 1.76 |
| Ciclosporin or FK-506 | 258 (0.5) | 80 (0.1) | 8.65 | 6.73 to 11.12 | 7.93 | 5.97 to 10.54 |