1 | F | Systemic | 2 | 33 | Fever, arthralgia, rash | Etanercept 25 mg ×2/week | PDN 80 mg/day | Remission | None | 5 months. Anti-TNF stopped (other: drug availability) |
2 | F | Articular | 5 | 55 | Fever, polyarthritis, rash | Etanercept 25 mg ×2/week | AZA 100 mg/day PDN 30 mg/day | Partial response | Isolated fever | 12 months. Anti-TNF stopped (lack of efficacy) |
Infliximab 5 mg/kg | AZA 100 mg/day MethylPDN 1g PDN 30 mg/day | Partial response | Isolated fever | 10 months. Anti-TNF stopped (lack of efficacy) |
3 | M | Articular | 7 | 55 | Polyarthritis | Etanercept 25 mg ×2/week | IV Ig1 | Failure | Polyarthritis | 3 months. Anti-TNF stopped (lack of efficacy) |
4 | F | Articular | 5 | 36 | Fever, polyarthritis, fatigue | Etanercept 25 mg ×2/week | PDN 20 mg/day | Partial response | Oligoarthritis | 43 months. Anti-TNF ongoing |
5 | F | Articular | 17 | 29 | Polyarthritis | Infliximab 3 mg/kg | MTX | Failure | Polyarthritis | 1 month. Anti-TNF stopped (side effects) |
6 | F | Systemic | 2 | 74 | Fever, arthralgia, rash | Infliximab 5 mg/kg | PDN 20 mg/day MTX 15 mg/week | Partial response | Rash, arthralgia | 1 month. Anti-TNF stopped (side effects) |
7 | M | Articular | 17 | 28 | Fever, polyarthritis, myalgia | Infliximab 3 mg/kg | PDN 40 mg/day MTX 7.5 mg/week | Failure | Fever, arthritis, myalgia Polyarthritis, myalgia | 2 months. Anti-TNF stopped (side effects) |
Rash | Etanercept 25 mg ×2/week | PDN 40 mg/day MTX 7.5 mg/week | Partial response | Rash, arthralgia | 1 month. Anti-TNF stopped (side effects) |
8 | F | Articular | 6 | 61 | Polyarthritis, rash | Infliximab 3 mg/kg | PDN 10 mg/day MTX 17.5 mg/week | Remission | None | 44 months. Anti-TNF ongoing |
9 | F | Articular | 4 | 44 | Polyarthritis | Infliximab 3 mg/kg | PDN 50 mg/day MTX 15 mg/week | Partial response | Few arthritis | 34 months. Anti-TNF ongoing |
10 | F | Systemic | 2 | 73 | Fever, arthralgia, fatigue | Infliximab 3 mg/kg | PDN MTX 15 mg/week | Partial response | Arthralgia, fatigue | 12 months. Anti-TNF stopped (lack of efficacy) |
11 | F | Articular | 21 | 32 | Fever, polyarthritis, rash | Etanercept | PDN 15 mg/day MTX 7.5 mg/week | Partial response | Few arthritis | 10 months. Anti-TNF stopped (lack of efficacy) |
25 mg ×2/week |
| Infliximab 3 mg/kg | PDN 12 mg/day MTX 7.5 mg/week | Partial response | Few arthritis | 7 months. Anti-TNF stopped (lack of efficacy) |
12 | M | Articular | 12 | 29 | Fever, polyarthritis, rash | Infliximab 3 mg/kg | MTX 15 mg/week | Remission | None | 12 months. Anti-TNF stopped(lack of efficacy) |
13 | F | Articular | 2 | 18 | Polyarthritis | Etanercept | PDN 10 mg/day | Partial response | Few arthritis | 35 months. Anti-TNF ongoing |
Fatigue | 25 mg ×2/week | MTX 10 mg/week | | |
14 | M | Articular | 3 | 25 | Polyarthritis, rash | Infliximab 3 mg/kg | PDN 10 mg/day | Remission | None | 16 months. Anti-TNF ongoing |
MTX 15 mg/week | | |
15 | F | Articular | 12 | 29 | Fever, arthralgia | Infliximab 3 mg/kg | PDN 5 mg/day MTX 12.5 mg/week | Remission | None | 36 months. Anti-TNF ongoing |
16 | F | Systemic | 14 | 37 | Fever, arthralgia, rash | Infliximab 3 mg/kg | PDN 20 mg/day AZA 150 mg/day | Partial response | Arthralgia, rash | 9 months. Anti-TNF stopped (lack of efficacy) |
17 | M | Articular | 5 | 18 | Fever, polyarthritis | Etanercept 25 mg ×2/week | PDN 20 mg/day | Partial response | Few arthritis | 9 months. Anti-TNF stopped (lack of efficacy) |
| Infliximab 3 mg/kg | PDN 15–20 mg/day MT X 7.5 mg/week | Partial response | Few arthritis | 3 months. Anti-TNF ongoing (lack of efficacy) |
18 | F | Articular | 11 | 46 | Fever, polyarthritis | Etanercept 25 mg ×2/week | PDN 15– 20 mg/day MTX 20 mg/week | Partial response | Few arthritis | 6 months. Anti-TNF ongoing |
19 | F | Systemic | 7 | 32 | Fever, polyarthritis, rash | Etanercept 25 mg ×2/week | PDN 15– 20 mg/day | Failure | Fever, arthritis, rash | 3 months, Anti-TNF stopped (lack of efficacy) |
Sore throat | Infliximab 3 mg/kg | PDN 15– 20 mg/day | Partial response | Few arthritis, rash | 4 months. Anti-TNF stopped (other: serious burn) |
20 | F | Articular | 15 | 60 | Fever, polyarthritis, rash | Infliximab 3 mg/kg | PDN 45 mg/day MTX 17.5 mg/week | Partial response | Few arthritis | 8 months. Anti-TNF ongoing |