Serious events during etanercept treatment within selected diagnostic groups
| Adverse event | n | /1000 patient-years* |
|---|---|---|
| *Total observation time was 2693.6 patient-years. | ||
| Infections | ||
| Sepsis | 8 | 3.0 |
| Pneumonia | 8 | 3.0 |
| Osteitis | 3 | 1.1 |
| Infectious arthritis | 2 | 0.7 |
| Soft tissue abscess | 2 | 0.7 |
| Gastroenteritis | 2 | 0.7 |
| Recurrent fever | 1 | 0.4 |
| Skin inflammation | 1 | 0.4 |
| Encephalitis | 1 | 0.4 |
| Cardiovascular disorders | ||
| Myocardial infarction | 5 | 1.9 |
| Pulmonary oedema | 2 | 0.7 |
| Angina pectoris | 2 | 0.7 |
| Coronary artery disorder | 1 | 0.4 |
| Tachycardia | 1 | 0.4 |
| Asystole | 1 | 0.4 |
| Heart failure | 1 | 0.4 |
| Venous thrombosis | 1 | 0.4 |
| Other vascular disorder | 1 | 0.4 |
| Haematological disorders | ||
| Leucopenia | 4 | 1.5 |
| Thrombocytopenia | 2 | 0.7 |
| Pancytopenia | 1 | 0.4 |
| Myelodysplastic syndrome | 1 | 0.4 |
| Other haematological disorders | 1 | 0.4 |
| Neoplasms | ||
| Lymphoma | 3 | 1.1 |
| Benign respiratory tract neoplasm | 2 | 0.7 |
| Unspecified liver neoplasm | 1 | 0.4 |
| Primary liver cancer | 1 | 0.4 |
| Benign gastrointestinal neoplasm | 1 | 0.4 |
| Ovarian cancer | 1 | 0.4 |
| Cervical cancer | 1 | 0.4 |
| Rectal cancer | 1 | 0.4 |
| Neurological disorders | ||
| Paraesthesiae | 2 | 0.7 |
| Subarachnoid haemorrhage | 2 | 0.7 |
| Cerebral infarction | 1 | 0.4 |
| Facial paresis | 1 | 0.4 |
| Dysarthria | 1 | 0.4 |
| Headache | 1 | 0.4 |