Table 1

 Detection of viral genomic copies in injected joints after intra-articular injection of rAAV2 or rAAV5

rAAV2rAAV5
Genomic DNA was isolated from crushed ankle joints 1, 2, 3, or 4 weeks after injection. Quantitative PCR was performed with specific primers for the CMV promoter of the transgene. Values are expressed as mean (SD) GC/μg gDNA.
Week 16.45×104 (2.12×103)1.42×107 (3.39×103)
Week 21.83×103 (5.87×102)1.37×106 (5.17×103)
Week 3<10 copies4.37×106 (2.25×103)
Week 4<10 copies2.24×105 (1.49×103)