Table 3

 The estimated cut off points of DAS28 corresponding to the ARA and the clinical remission criteria

CharacteristicsRemission criteria
ARA*ARA†Clinical
(95% CI)(95% CI)(95% CI)
*ARA remission criteria, all the five criteria must be fulfilled (fatigue excluded); †ARA remission criteria, four of the five criteria must be fulfilled (fatigue excluded); ‡area under the receiver operating characteristic curves. 95% confidence interval obtained by bias corrected and accelerated bootstrapping (5000 replications); §positive predictive value (proportion of the subjects who had positive test results who were in remission); ¶likelihood ratio positive (ratio of the sensitivity of a test to the false positive error rate of the test).
Cut off point2.322.602.68
Area under ROC curves‡0.87 (0.82 to 0.93)0.89 (0.83 to 0.94)0.90 (0.84 to 0.94)
Sensitivity (%)100 (82 to 100)93 (80 to 98)91 (80 to 97)
Specificity (%)73 (64 to 80)76 (67 to 83)79 (70 to 87)
PPV§ (%)33 (21 to 46)56 (43 to 68)69 (57 to 80)
LR+¶3.64 (2.66 to 4.71)3.80 (2.76 to 5.32)4.38 (3.05 to 6.48)