Table 1

 Drugs used at the time of arthroscopy

Patient No, ResponseBefore HDC + ASCT, at the time of the first arthroscopyDAS3 Months after HDC + ASCT, at the time of the second arthroscopyDAS1 Year after HDC + ASCT, at the time of the third arthroscopyDAS
Drug, doseDrug, doseDrug, dose
Four variable Disease Activity Score (DAS)  =  (0.54 × √ Ritchie articular index) + (0.065 × number of swollen joints) + (0.33×ln ESR) + (0.0072 × patient disease activity VAS).
1, goodCiclosporin 300 mg/day5.88Prednisone 7.5 mg/day2.11Methotrexate 7.5 mg/week2.78
Prednisone 10 mg/dayKetoprofen 400 mg/dayKetoprofen 200 mg/day
Ketoprofen 400 mg/day
2, goodPrednisone 10 mg/day4.31None0.89None2.62
Piroxicam 20 mg/day
3, goodHydroxychloroquine 200 mg/day4.99None2.28Ibuprofen 1200 mg/day2.47
Ciclosporin 100 mg/day
Ibuprofen 1200 mg/day
4, moderateMethotrexate 17.5 mg/week6.61Prednisone 7.5 mg/day3.85Leflunomide 20 mg4.60
Ciclosporin 150 mg/dayNaproxen 1000 mg/dayPrednisone 10 mg/day
Prednisone 10 mg/dayNaproxen 1000 mg/day
Naproxen 1000 mg/day
5, goodMethotrexate 15 mg/week5.58Diclofenac 150 mg/day2.05Methotrexate 15 mg/week2.78
Diclofenac 150 mg/dayIbuprofen 800 mg/day
6, noPrednisone 10 mg/day4.71Prednisone 5 mg/day5.16Methotrexate 17.5 mg/week4.67
Ibuprofen 1600 mg/dayIbuprofen 1600 mg/dayPrednisone 7.5 mg/week
Ibuprofen 1600 mg/day
Tramadol 150 mg/day
7, goodMethotrexate 20 mg/week5.88Diclofenac 150 mg/day2.11Methotrexate 10 mg/week3.26
Ciclosporin 100 mg/dayDiclofenac 150 mg/day
Diclofenac 150 mg/day