Table 1

 Demographic and mean (or median) baseline characteristics (and ranges) of 45 patients with active ankylosing spondylitis

CharacteristicPlacebo (n = 15)Leflunomide (n = 30)
*Number of patients with at least one swollen joint.
BASDAI, Bath ankylosing spondylitis disease activity index; ESR, erythrocyte sedimentation rate.
Male sex (%)10 (67)22 (73)
% HLA-B27 positive100 (14/14)81 (21/26)
Age (years)39 (25 to 58)42 (22 to 66)
Median disease duration (years)5.7 (0.3 to 14.1)9.4 (0.3 to 38.6)
Peripheral arthritis (%)*2(13)2 (7)
BASDAI (0–10)5.9 (2.9 to 9.7)6.4 (2.7 to 9.5)
ESR (mm/h)18 (2 to 54)22 (2 to 66)