Change from baseline in ACR components at 24 weeks
| Anakinra + MTX (n = 250) | Placebo + MTX (n = 251) | |
|---|---|---|
| Results are shown as mean change from baseline (SE). | ||
| *p<0.05; **p<0.01; ***p<0.001. | ||
| SE, standard error; MTX, methotrexate; CRP, C reactive protein; ESR, erythrocyte sedimentation rate. | ||
| Swollen joint count (0–66) | −6.8 (0.6) | −6.5 (0.6) |
| Tender or painful joint count (0–68) | −12.0** (0.9) | −8.7 (0.9) |
| Physician’s assessment of disease activity (0–100) | −25.2* (1.5) | −20.1 (1.5) |
| Patient’s assessment of disease activity (0–100) | −17.7*** (1.6) | −8.9 (1.7) |
| Patient’s assessment of pain (0–100) | −19.0** (1.7) | −11.7 (1.8) |
| Health Assessment Questionnaire score (0–3) | −0.29* (0.03) | −0.18 (0.03) |
| Log transformed CRP (mg/l) | −5*** (0.3) | −1 (0.4) |
| ESR (mm/1st h) | −16.2*** (1.2) | −6.0 (1.3) |