Longitudinal modelling of remission time-averaged odds ratios (ORs) using generalised estimating equations (GEE) for DAS and DAS28, week 8 through 52
| Imputation method | Combination vMTX† | Combination vETN† | ETN v MTX‡ |
|---|---|---|---|
| Results are shown as OR (95% CI). | |||
| *Non-response imputation assigns all missing time point values as not in remission; †p<0.0001; ‡not significant. | |||
| DAS remission | |||
| None | 3.26 (2.15 to 4.93) | 2.57 (1.72 to 3.84) | 1.26 (0.86 to 1.99) |
| LOCF | 3.37 (2.26 to 5.04) | 2.58 (1.75 to 3.79) | 1.31 (0.84 to 2.03) |
| Non-response* | 3.49 (2.34 to 5.20) | 2.31 (1.58 to 3.37) | 1.51 (0.98 to 2.33) |
| DAS28 remission | |||
| None | 3.70 (2.44 to 5.61) | 2.56 (1.75 to 3.75) | 1.45 (0.92 to 2.27) |
| LOCF | 3.45 (2.36 to 5.06) | 2.60 (1.78 to 3.77) | 1.33 (0.87 to 2.05) |
| Non-response* | 3.78 (2.62 to 5.46) | 2.67 (1.86 to 3.82) | 1.42 (0.94 to 2.14) |