Table 4

 Number (%) of patients achieving sustained response over 6 months

VariableMethotrexate (n = 228)Etanercept (n = 223)Etanercept + methotrexate (n = 231)p Value
*ACR70 response continuously for 6 months; †DAS remission continuously for 6 months; ‡DAS28 remission continuously for 6 months.
Major clinical response*13 (5.7)22 (9.9)55 (23.8)<0.0001
Sustained DAS remission†14 (6.1)13 (5.8)39 (16.9)<0.0001
Sustained DAS28 remission‡8 (3.5)12 (5.4)41 (17.9)<0.0001