Number (%) of patients achieving sustained response over 6 months
| Variable | Methotrexate (n = 228) | Etanercept (n = 223) | Etanercept + methotrexate (n = 231) | p Value |
|---|---|---|---|---|
| *ACR70 response continuously for 6 months; †DAS remission continuously for 6 months; ‡DAS28 remission continuously for 6 months. | ||||
| Major clinical response* | 13 (5.7) | 22 (9.9) | 55 (23.8) | <0.0001 |
| Sustained DAS remission† | 14 (6.1) | 13 (5.8) | 39 (16.9) | <0.0001 |
| Sustained DAS28 remission‡ | 8 (3.5) | 12 (5.4) | 41 (17.9) | <0.0001 |