Pooled index | 20% Improvement response | z scores* | |||
---|---|---|---|---|---|
Leflunomide | Methotrexate | Placebo | Leflunomide v placebo | Methotrexate v placebo | |
*All z scores p<0.001. | |||||
Source: Pincus et al. Arthritis Rheum 2003;48:625–30.48 | |||||
ACR 20 | 52% | 46% | 26% | 4.36 | 3.32 |
Patient only | 64% | 56% | 33% | 4.85 | 3.00 |
Assessor only | 74% | 69% | 43% | 5.12 | 4.86 |
All Core Data Set | 57% | 49% | 29% | 5.89 | 5.12 |
DAS | 59% | 59% | 30% | 4.84 | 4.85 |