Table 1

 Literature search and retrieval of relevant randomised controlled trials (RCTs)

StageNumber of studiesReferences
Raw citations from all sources420
RCTs reviewed for inclusion criteria296, 8–13, 23–44
Non-placebo and non-NSAID comparisons−528–32
Paracetamol combination v other agents−1233–44
Duplicate publications−211, 12
RCTs met inclusion criteria106, 8–10, 13, 23–27
Paracetamol v placebo26, 27
Paracetamol v NSAIDs v placebo213, 25
Paracetamol v NSAIDs68–10, 23, 24, 26