Outcome of patients with hip or knee OA from baseline to the 6 months’ follow up (n = 128)
| Baseline | 1 Month | 6 Months | ||||||
|---|---|---|---|---|---|---|---|---|
| Mean | (SD) | Mean | (SD) | ES (95% CI) | Mean | (SD) | ES (95% CI) | |
| *p<0.05. | ||||||||
| ES, effect size (score at follow up − score at baseline)/standard deviation at baseline; PF, physical functioning; RF, role physical; BP, bodily pain; GH, general health; VT, vitality; SF, social functioning; RE, role emotional; MH, mental health; PCS, physical component scale; MCS, mental component scale. | ||||||||
| WOMAC scales: 0 = no symptoms, 10 = maximal symptoms; SF-36 scales: 0 = worst health, 100 = best health. | ||||||||
| Wilcoxon signed ranks test, p one-tailed, null hypothesis: difference (mean at follow up minus mean at baseline = entry into the clinic) = zero; p>0.05: we accept the null hypothesis at type I error = 5%—for example, there is no difference. | ||||||||
| The equation for the CI of the ES is not equivalent to the Wilcoxon signed rank test. Therefore in a few cases the CI contains 0, although the Wilcoxon signed rank test is significant. | ||||||||
| WOMAC | ||||||||
| Pain | 4.49 | (2.18) | 3.27* | (1.98) | 0.56 (0.31 to 0.80) | 3.93* | (2.22) | 0.26 (0.01 to 0.50) |
| Stiffness | 4.55 | (2.61) | 3.56* | (2.21) | 0.38 (0.13 to 0.63) | 4.31 | (2.54) | 0.09 (−0.15 to 0.34) |
| Function | 4.30 | (2.17) | 3.34* | (1.99) | 0.44 (0.19 to 0.69) | 3.96* | (2.18) | 0.16 (−0.09 to 0.40) |
| Global | 4.36 | (2.10) | 3.34* | (1.93) | 0.49 (0.23 to 0.74) | 4.00* | (2.13) | 0.17 (−0.07 to 0.42) |
| SF-36 | ||||||||
| PF | 39.8 | (20.1) | 45.8* | (21.8) | 0.30 (0.05 to 0.55) | 43.5* | (21.6) | 0.18 (−0.06 to 0.43) |
| RP | 24.6 | (33.6) | 32.9* | (39.9) | 0.25 (0.00 to 0.49) | 30.8 | (38.7) | 0.18 (−0.06 to 0.43) |
| BP | 29.9 | (17.1) | 38.8* | (18.2) | 0.52 (0.27 to 0.77) | 36.3* | (20.0) | 0.37 (0.12 to 0.62) |
| GH | 57.2 | (19.9) | 59.4 | (18.8) | 0.11 (−0.13 to 0.36) | 55.1 | (19.0) | −0.11 (−0.35 to 0.14) |
| VT | 45.9 | (19.4) | 50.8* | (19.4) | 0.25 (0.01 to 0.50) | 45.7 | (21.3) | −0.01 (−0.26 to 0.23) |
| SF | 69.4 | (25.6) | 75.2* | (24.6) | 0.23 (−0.02 to 0.47) | 67.9 | (25.5) | −0.06 (−0.30 to 0.19) |
| RE | 53.9 | (44.5) | 56.8 | (45.5) | 0.07 (−0.18 to 0.31) | 54.6 | (46.5) | 0.02 (−0.23 to 0.26) |
| MH | 66.3 | (18.8) | 69.8* | (17.9) | 0.19 (−0.06 to 0.43) | 65.0 | (20.4) | −0.07 (−0.31 to 0.18) |
| PCS | 30.3 | (8.3) | 33.4* | (8.5) | 0.37 (0.12 to 0.62) | 32.4* | (9.1) | 0.25 (0.01 to 0.50) |
| MCS | 49.2 | (11.9) | 50.7 | (11.5) | 0.13 (−0.12 to 0.37) | 48.1 | (12.9) | −0.09 (−0.34 to −0.15) |