FACS analysis of a panel of membrane markers on iDC and mDC
| CD Marker | Immature DC | Mature DC | ||||||
|---|---|---|---|---|---|---|---|---|
| Controls (n = 32) | RA (n = 31) | Controls (n = 10) | RA (n = 11) | |||||
| % Cells | MFI | % Cells | MFI | % Cells | MFI | % Cells | MFI | |
| Results are shown as mean (SD). | ||||||||
| CD14 | 13 (16) | 24 (13) | 24 (21) | 38 (30) | 5 (4) | 17 (13) | 9 (7) | 19 (14) |
| DC-SIGN | 78 (11) | 52 (33) | 88 (9) | 62 (29) | 76 (11) | 42 (18) | 73 (13) | 48 (16) |
| CD80 | 53 (24) | 31 (17) | 64 (23) | 24 (15) | 92 (8) | 78 (23) | 88 (8) | 81 (22) |
| CD83 | 9 (8) | 23 (15) | 7 (6) | 17 (14) | 81 (9) | 65 (10) | 83 (8) | 77 (10) |
| CD86 | 66 (24) | 85 (25) | 68 (22) | 75 (21) | 94 (6) | 157 (26) | 90 (10) | 166 (23) |
| MHC-I | 95 (23) | 139 (21) | 96 (10) | 141 (19) | 94 (7) | 394 (33) | 89 (7) | 391 (45) |
| MHC-II DQ | 78 (17) | 89 (18) | 80 (22) | 75 (18) | 86 (14) | 143 (87) | 80 (21) | 138 (33) |
| MHC-II DP/DR | 77 (21) | 74 (16) | 81 (19) | 63 (18) | 87 (19) | 170 (32) | 87 (13) | 149 (21) |