Table 3

Predictive factors for persistent remission (DAS <1.6 at the three year and five year evaluations)

Baseline variablep Value*OR (95% CI)*
*Significance level calculated using the χ2 test with Yates’ correction.
†Range 24–125 ng/ml.
‡DRB1*04 includes *0401, 0404, 0405, and 0408.
Anti-CCP, anti-cyclic citrullinated protein; CI, confidence interval; DAS, disease activity score; ESR, erythrocyte sedimentation rate; HAQ, health assessment questionnaire; OR, odds ratio; RF, rheumatoid factor.
DAS <40.00034.8 (1.9 to 11.9)
C reactive protein <14.5 mg/l0.0103 (1.2 to 7.3)
Ritchie score <170.0162.8 (1.2 to 6.8)
HAQ score <1.250.0183.2 (1.1 to 8.9)
IgM RF negativity0.022.6 (1.1 to 6.3)
Morning stiffness <60 min0.042.7 (1.0 to 7.4)
Total Sharp score <40.042.3 (1.0 to 5.7)
Anti-HSP90 negativity0.063.2 (0.9 to 11.4)
IgA RF negativity0.102 (0.85 to 5.1)
Pain on visual analogue scale <59 mm0.132 (0.8 to 5.0)
Antikeratin antibody negativity0.161.94 (0.75 to 5.0)
Tender joint count <210.191.8 (0.7 to 4.6)
Anticalpastatin antibody negativity0.290.58 (0.2 to 1.3)
Swollen joint count <90.511.3 (0.57 to 3.0)
ESR <28 mm/h0.561.2 (0.5 to 2.9)
Anti-CCP antibody negativity0.621.25 (0.5 to 4.7)
YKL40 negativity†0.740.7 (0.07 to 6.3)
Erosion score  = 00.82.18 (0.9 to 5.3)
HLA-DRB1*01 negativity0.80.89 (0.36 to 2.2)
HLA-DRB1*04 negativity‡0.91.05 (0.5 to 2.4)