Table 1

Characteristics of 191 patients with rheumatoid arthritis

Values are the mean (SD) unless stated otherwise.
Positive cut off values were as follows: IgM rheumatoid factor (RF), ⩾20 IU/ml; IgA RF, ⩾7 units/ml; antiperinuclear antibodies, ⩾1:20; anti-cyclic citrullinated protein antibodies, ⩾50 units/ml; antikeratin antibodies, ⩾1:80; anticalpastatin antibodies, ⩾15 units/ml; antinuclear antibodies, ⩾1:160.
Anti-CCP, anti-cyclic citrullinated protein; anti-HSP 90, anti-heat-shock protein 90 kDa antibodies; DAS, disease activity score; ESR, erythrocyte sedimentation rate; HAQ, health assessment questionnaire; RF, rheumatoid factor.
†DRB1*04 includes DRB1*0401, 0404, 0405, and 0408.
‡Total damage score on radiographic evaluation of the hands and feet.
Sex, % women73.3%
Age at diagnosis (years)50.5 (14.7)
Duration of disease (months)3.3 (2.6)
Morning stiffness (min)84 (79.4)
Patient’s assessment of pain (visual analogue scale) (mm)57.5 (22.2)
Swollen joints (number)9.0 (5.9)
Tender joints (number)21 (10)
Ritchie score17.5 (8.5)
HAQ score1.3 (0.7)
DAS4.1 (0.8)
Extra-articular manifestations (% patients)8.4%
ESR (mm/h)40.2 (28.5)
C reactive protein (mg/l)34.1 (43.2)
RF positivity (% patients)80.8%
IgM RF (%)68.0%
IgA RF (%)75.5%
Antibody positivity, % patients
YKL40 serum concentration (ng/ml)109.7 (79.9)
HLA-DRB1*04 (% patients)†47.6%
HLA-DRB1*01 (% patients)29.5%
Total Sharp score at baseline‡3.6 (7.7)