Expression of activation markers on CD3+CD4+ lymphocytes
| % CD4+HLA-DR+ | % CD4+CD25+ | % CD4+CD69+ | % CD4+CD45Ro+ | |||||
|---|---|---|---|---|---|---|---|---|
| HC | SSc | HC | SSc | HC | SSc | HC | SSc | |
| Results are shown as mean (SD). | ||||||||
| NAD, non-adherent; BND, bound; MIG, migrated. | ||||||||
| *Denotes p<0.05 (unpaired t test) between SSc and HC lymphocyte fractions. | ||||||||
| Ex vivo | 5 (3) | 7 (6) | 13 (6) | 19 (13) | 7 (9) | 6 (5) | 61 (17) | 66 (15) |
| NAD | 4 (2) | 6 (5) | 13 (3) | 21 (12) | 3 (3) | 6 (6) | 57 (12) | 59 (16) |
| BND | 10 (7) | 14 (12) | 16 (9) | 28 (19) | 8 (10) | 3 (3) | 65 (16) | 70 (15) |
| MIG | 14 (10)* | 31 (23)* | 36 (37) | 31 (38) | 23 (24) | 4 (6) | 74 (9) | 77 (10) |