Table 1

Quantification of cathepsin K expression during early cartilage degeneration.

ControlDel1
Significance of the results was analysed by non-parametric Mann-Whitney U test: *p<0.05; **p<0.01; ***p<0.001.
†Results are shown as mean (SD) at the age of 4 months; ‡n, denotes the number of samples used.
Cartilage erosion grade0.37 (0.49)†, n = 30‡1.82 (0.80), n = 22***
Relative cathepsin K mRNA levels0.16 (0.08), n = 60.35 (0.06), n = 6*
Relative number of chondrocytes expressing cathepsin K0.34 (0.06), n = 60.46 (0.04), n = 6**