Control | Del1 | |
---|---|---|

Significance of the results was analysed by non-parametric Mann-Whitney U test: *p<0.05; **p<0.01; ***p<0.001. | ||

†Results are shown as mean (SD) at the age of 4 months; ‡n, denotes the number of samples used. | ||

Cartilage erosion grade | 0.37 (0.49)†, n = 30‡ | 1.82 (0.80), n = 22*** |

Relative cathepsin K mRNA levels | 0.16 (0.08), n = 6 | 0.35 (0.06), n = 6* |

Relative number of chondrocytes expressing cathepsin K | 0.34 (0.06), n = 6 | 0.46 (0.04), n = 6** |