Table 4

Odds ratios (ORs) of vertebral deformities (1995–96) and relative risks (RRs) of incident non-vertebral fractures (1992–99) by COLIA1 genotype (GG v GT+TT) in men and women

GenotypeVertebral deformity (n = 502)Any non-vertebral fracture (n = 937)
No (%)Crude OR (95% CI)Adjusted* OR (95% CI)No (%)Crude RR (95% CI)Adjusted† RR (95% CI)
*Adjusted for age, body weight and lumbar spine BMD; †adjusted for age and body weight; ‡for 256 of the 258 men with radiographs, data were available on age, body weight and lumbar spine BMD; §for 246 of the 259 women with radiographs, data were available on age, body weight, and lumbar spine BMD; ¶for 457 of the 464 men with fracture follow up, data were available on age and body weight; **for 480 of the 492 women with fracture follow up, data were available on age and body weight.
Menn = 256‡n = 457¶
GG26/173 (15)1.01.022/301 (7)1.01.0
(GT+TT)16/83 (19)1.4 (0.7 to 2.7)1.5 (0.7 to 3.0)6/156 (4)0.5 (0.2 to 1.3)0.5 (0.2 to 1.3)
Womenn = 246§n = 480**
GG36/180 (20)1.01.039/335 (12)1.01.0
(GT+TT)12/66 (18)0.9 (0.4 to 1.8)0.9 (0.4 to1.8)18/145 (12)1.1 (0.6 to 1.9)1.1 (0.6 to 1.9)