Table 3

Means (SEM) of hip and lumbar spine BMD and total body BMC according to COLIA1 Sp1 genotype, stratified by sex, in the subsample with DXA measurements

Skeletal siteMen (n = 255)*ANOVAWomen (n = 252)†ANOVA
GG (n = 173)GT (n = 70)TT (n = 12)p valueGG (n = 186)GT (n = 61)TT (n = 5)p value
All values are presented as means (SEM); in men, values were adjusted for age, height, body weight, Kellgren score, and alcohol use; in women values were adjusted for age, height, body weight, Kellgren score, and age at menopause.
*For 255 of the 256 men with DXA measurements, data were available on age, body weight, and alcohol use; †for 252 of the 256 women with DXA measurements, data were available on age, body weight, and age at menopause.
Total hip (g/cm2)0.91 (0.01)0.92 (0.02)0.90 (0.04)0.940.79 (0.01)0.78 (0.01)0.74 (0.05)0.50
Femoral neck (g/cm2)0.74 (0.01)0.74 (0.01)0.74 (0.03)0.990.66 (0.01)0.67 (0.01)0.69 (0.04)0.81
Trochanter (g/cm2)0.72 (0.01)0.72 (0.01)0.70 (0.03)0.830.61 (0.01)0.60 (0.01)0.55 (0.04)0.25
Lumbar spine (g/cm2)1.03 (0.01)1.04 (0.02)1.10 (0.05)0.250.91 (0.01)0.91 (0.02)0.96 (0.07)0.67
Total body BMC (g)2460 (23.0)2491 (35.9)2520 (85.8)0.571834 (18.9)1793 (33.3)1781 (126.8)0.55