Results of secondary addition of MTX to etanercept
| MTX duration (months) | ||||||
|---|---|---|---|---|---|---|
| 0 | 3 | 6 | 9 | 12 | Friedman; p value | |
| ACR20 (%) | 56 | 61 | 67 | 67 | ||
| ACR50 (%) | 28 | 28 | 39 | 50 | ||
| ACR70 (%) | 11 | 6 | 17 | |||
| DAS28, mean | 4.9 | 3.0 | 2.9 | 2.8 | 2.4 | 0.0017 |
| Score HAQ, mean | 1.7 | 1.3 | 1.2 | 1.2 | 1.1 | 0.0081 |
| ESR (mm/1st h), mean | 49.1 | 33.2 | 30.6 | 33.8 | 27.2 | 0.1266 |
| CRP (mg/l), mean | 56.6 | 24.0 | 13.8 | 17.1 | 12.3 | 0.0001 |