Percentage change in mean hsCRP according to selected characteristics in 770 consecutive patients with hip or knee joint replacement due to advanced OA estimated from multivariable linear regression
| Characteristics | Change in mean hsCRP (%) | (95% CI)* |
|---|---|---|
| *95% Confidence interval for percentage change in geometric mean serum hsCRP level estimated from multivariable linear regression with log transformed hsCRP as dependent variable controlling (adjusting) for all variables presented in the table; †weight in kg divided by squared height in m; ‡systolic and/or diastolic blood pressure ⩾160 or ⩾95 mmHg, respectively, and/or use of antihypertensive drugs; §medical history; ¶history of diabetes or use of oral antidiabetics or insulin; **VAS from 0 (no pain) to 100 (extreme pain). | ||
| Age (10 year increase) | 9.3 | (−0.4 to 19.9) |
| Body mass index (5 unit increase)† | 22.3 | (12.1 to 33.4) |
| Female sex | 25.9 | (3.7 to 52.8) |
| Comorbidity | ||
| Hypertension‡ | 3.7 | (−12.7 to 23.2) |
| Coronary artery disease | 14.0 | (−9.8 to 44.0) |
| Congestive heart failure§ | 2.9 | (−16.1 to 26.2) |
| Diabetes¶ | 11.4 | (−13.8 to 44.0) |
| Use of diuretics | 34.0 | (9.9 to 63.3) |
| Smoking | ||
| Former | 35.8 | (13.6 to 62.5) |
| Current | 92.2 | (51.4 to 144) |
| Alcohol consumption | ||
| None | 0.0 | Reference |
| <10 g/day | −2.8 | (−23.3 to 23.2) |
| ⩾10 g/day | −5.5 | (−28.4 to 24.8) |
| Intensity of pain (10 mmVAS** increase) | 5.7 | (1.1 to 10.4) |
| Intensity of pain (mmVAS**, separate model) | ||
| ⩽58 | 0.0 | Reference |
| 59–⩽69 | 13.7 | (−9.0 to 42.1) |
| 70–⩽78 | 17.0 | (−6.8 to 46.9) |
| 79–⩽87 | 20.0 | (−4.5 to 50.8) |
| ⩾88 | 35.5 | (7.4 to 70.8) |
| Additional painful joint regions | 17.0 | (−1.8 to 39.5) |