Description of 770 consecutive patients with hip or knee joint replacement due to advanced OA
| *Weight divided by height squared; †systolic and/or diastolic blood pressure ⩾160 or ⩾95 mm Hg, respectively, and/or use of antihypertensive drugs; ‡medical history; §estimated (according to Cockcroft and Gault formula18) creatinine clearance below 60 ml/min (15th centile of overall distribution), information available for 768 patients; ¶ medical history of gout or use of uricosuric/uricostatic drugs; **history of diabetes or use of oral antidiabetics or insulin; ††women only. | |
| Age (years), mean (SD) | 63 (9) |
| Body mass index (kg/m2), mean (SD)* | 28 (4) |
| Women, No (%) | 481 (62.5) |
| Comorbidity, No (%) | |
| Hypertension† | 391 (50.8) |
| Coronary artery disease‡ | 92 (11.9) |
| Congestive heart failure‡ | 146 (19.0) |
| Impaired renal function§ | 117 (15.2) |
| Gout¶ | 104 (13.5) |
| Diabetes** | 73 (9.5) |
| Drug use, No (%) | |
| NSAIDs | 345 (44.8) |
| Diuretics | 186 (24.2) |
| ACE inhibitors | 106 (13.8) |
| Lipid lowering agents | 35 (4.5) |
| Hormone replacement therapy†† | 59 (12.3) |
| Heavy physical exertion (work or leisure), No (%) | 210 (27.3) |
| Smoking | |
| Never | 445 (57.8) |
| Former | 227 (29.5) |
| Current | 98 (12.7) |
| Alcohol consumption | |
| None | 89 (11.6) |
| <10 g/day | 413 (53.8) |
| ⩾ = 10 g/day | 266 (34.6) |