Reproducibility of BMD (g/cm2) measurement in postmenopausal women (n = 95) and children (n = 23)
Postmenopausal women | Children | |||||
---|---|---|---|---|---|---|
L1–4 | Femoral neck | Total hip | L1–4 | Femoral neck | Total hip | |
Mean difference, mean of the difference between the first and the second BMD measurement; SDdifference, SD of the difference between the first and the second BMD measurement; SDD, smallest detectable difference (g/cm2); CV, coefficient of variation (%); LSC, least significant change (%); ICC, intraclass correlation coefficient. | ||||||
SDdifference and SDD are rounded off to two decimal places in the text of the article. | ||||||
Bland and Altman’s methods | ||||||
Mean difference (95% CI) (systematic bias) | −0.001 (−0.05 to 0.05) | −0.0008 (−0.04 to 0.04) | −0.0004 (−0.04 to 0.04) | −0.0009 (−0.02 to 0.02) | −0.004 (−0.05 to 0.04) | −0.003 (−0.03 to 0.02) |
SDdifference (random measurement error) | 0.0238 | 0.0220 | 0.0184 | 0.0088 | 0.0122 | 0.0116 |
SDD ~95% limits of agreement (assuming no systematic bias) | ±0.0466 | ±0.0432 | ±0.0361 | ±0.0172 | ±0.0238 | ±0.0228 |
CV (%) | 1.92 | 2.25 | 1.59 | 0.84 | 1.34 | 1.19 |
LSC (%) | 5.43 | 6.36 | 4.50 | 2.38 | 3.79 | 3.37 |
Random effects ICC (95% CI) | 0.99 (0.98 to 0.99) | 0.99 (0.98 to 0.99) | 0.99 (0.99 to 0.99) | 0.99 (0.99 to 1.00) | 0.99 (0.97 to 1.00) | 0.99 (0.99 to 1.00) |