Unadjusted risk of knee OA requiring arthroplasty and weight changes during different age periods
| Relative weight at the beginning and at the end of age range | From 20 to 30 years | From 30 to 40 years | From 40 to 50 years | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases (n = 229) | Controls (n = 424) | OR | 95% CI | Cases (n = 238) | Controls (n = 446) | OR | 95% CI | Cases (n = 248) | Controls (n = 375) | OR | 95% CI | |
| OR, odds ratio; CI, confidence interval. Normal, BMI ⩽25 kg/m2; overweight, BMI >25 kg/m2. Logistic regression modelling was used. | ||||||||||||
| Normal/normal | 154 | 313 | 1.00 | 104 | 280 | 1.00 | 70 | 242 | 1.00 | |||
| Normal/overweight | 49 | 61 | 1.63 | 1.07 to 2.49 | 60 | 70 | 2.30 | 1.52 to 3.48 | 40 | 66 | 2.09 | 1.30 to 3.36 |
| Overweight/normal | 3 | 17 | 0.35 | 0.10 to 1.24 | 1 | 8 | 0.33 | 0.04 to 2.72 | 6 | 7 | 2.96 | 0.96 to 9.10 |
| Overweight/overweight | 23 | 33 | 1.41 | 0.80 to 2.49 | 73 | 88 | 2.23 | 1.52 to 3.27 | 132 | 60 | 2.85 | 2.00 to 4.05 |