End points | Treatment group | ||
---|---|---|---|
25 mg BIIL 284 (n = 7) | 150 mg BIIL 284 (n = 9) | Placebo (n = 10) | |
Data represent mean (SD). | |||
TJC | |||
Baseline | 21.0 (7.4) | 17.1 (10.4) | 19.3 (6.9) |
Diff. from baseline | −0.3 (2.8) | 1.3 (4.2) | 0.0 (5.7) |
SJC | |||
Baseline | 12.3 (6.5) | 13.4 (9.8) | 12.0 (8.0) |
Diff. from baseline | −1.0 (6.2) | 0.2 (4.7) | 0.20 (3.0) |
ESR (mm/1st h) | |||
Baseline | 18.9 (8.3) | 35.6 (27.0) | 40.1 (56.5) |
Diff. from baseline | 3.4 (10.6) | 5.2 (19.8) | −2.3 (20.7) |
CRP (mg/l) | |||
Baseline | 4.9 (6.8) | 6.4 (7.3) | 9.37 (11.9) |
Diff. from baseline | −0.1 (0.8) | 10.4 (24.0) | 1.2 (4.9) |