The distribution of HLA-DM alleles in patients with antiphospholipid syndrome and controls
| Allele | APS (n = 186) | PAPS (n = 102) | SAPS (n = 84) | SLE APS (n = 80) | Controls (n = 218) | ||
|---|---|---|---|---|---|---|---|
| n = number of alleles in each group. | |||||||
| †p = 0.035, ‡p = 0.011 v controls by 4×2 χ2 test. | |||||||
| §p = 0.007 (pc = 0.028), ¶p = 0.003 (pc = 0.012) v controls by 2×2 χ2 test. | |||||||
| APS, antiphospholipid syndrome; PAPS, primary antiphospholipid syndrome; SAPS, secondary antiphospholipid syndrome; SLE, systemic lupus erythematosus. | |||||||
| DMA*0101 | 78.0% | † | 79.4% | 76.2% | ‡ | 88.8% | 85.8% |
| *0102 | 17.7§ | 14.7 | 21.4¶ | 8.8 | 8.3 | ||
| *0103 | 2.7 | 3.9 | 1.2 | 2.5 | 3.2 | ||
| *0104 | 1.6 | 2.0 | 1.2 | 0.0 | 2.8 | ||
| DMB*0101 | 75.8 | 75.5 | 76.2 | 75.0 | 69.7 | ||
| *0102 | 1.1 | 1.0 | 1.2 | 3.8 | 2.3 | ||
| *0103 | 22.0 | 22.5 | 21.4 | 21.3 | 25.7 | ||
| *0104 | 1.1 | 1.0 | 1.2 | 0.0 | 2.3 | ||
| *0105 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | ||