Table 1

 Distribution of onset subtypes of patients with juvenile idiopathic arthritis (JIA) and non-JIA diagnoses

DiagnosisNumber (% of JIA patients)
*Additional diagnoses in JIA patients were documented as follows: uveitis (20), episcleritis (2), seizures (1), atopic dermatitis (3), asthma (2), recurrent skin abscesses (1), osteoporosis (5), anaemia (1), chondritis of the patella (1), hyper-IgE syndrome (1), hemiparesis (1), IgA deficiency (5), sudden hearing loss (1), panniculitis (1), hepatitis (1), autoimmune hepatitis (1), idiopathic lung fibrosis (1), keratoconjunctivitis sicca (1), proteinuria (4), mitral insufficiency (1), amyloidosis (3), coeliac disease (1), transposition of the large arteries (1), renal venous thrombosis (1), chronic otitis media (1), chronic tonsillitis (1), recurrent urinary tract infection (1), proctitis (1), gastritis (4), arterial hypertonia (3), scoliosis (1), allergic sensitisation (1), gastro-oesophageal reflux disease (1), macrophage activation syndrome (1), pericarditis (1), cataract (1), ambylopia (1), Cushing’s disease (4), Kartagener’s syndrome (1), febrile seizures (1), aseptic bone necrosis (1), recurrent obstructive bronchitis (1).
Patients with non-JIA diagnoses were followed for safety items only.
CRMO, chronic recurrent multifocal osteomyelitis; NOMID, neonatal onset multisystemic inflammatory disease.
All JIA patients*322 (100%)
Systemic arthritis (systemic onset JIA)66 (21%)
Seronegative polyarticular JIA94 (29%)
Seropositive polyarticular JIA39 (12%)
Persistant oligoarticular JIA10 (3%)
Extended oligoarticular JIA54 (17%)
Enthesistis and arthritis JIA subtype26 (8%)
Psoriasis and arthritis JIA subtype17 (5%)
Unclassified JIA16 (5%)
Non-JIA diagnoses12
    Sarcoidosis3
    NOMID2
    Reactive arthritis2
    CRMO1
    Crohn’s disease1
    Behçet disease1
    Juvenile dermatomyositis1
    Uveitis (without JIA)1