Toxicities demonstrated in 16 patients with psoriatic arthritis treated with infliximab
| Toxicities (number of patients) | Details (number of patients) |
|---|---|
| Infections (6) | Pneumonia (2), septic arthritis (1), surgical site abscess (1), perichondritis (1), epididymitis (1) |
| Hepatic (4) | Transaminases >1.5×normal (4), concomitant MTX treatment (2) |
| GI–other than hepatic (3) | Lower gastrointestinal bleeding (2) |
| Diarrhoea (2) | |
| Allergic (3) | Urticaria (3), respiratory symptoms (2) |
| Haematological (1) | Thrombocytopenia (platelets 102×109/l) |
| Serological (9) | ANA seroconversion (8/12 seronegative at onset) |
| Anti-dsDNA seroconversion (6) | |
| ANA and dsDNA seroconversion (5) | |
| No clinical evidence of a connective tissue disease was seen | |
| Other (1) | Hydrocele |