Characteristics of cases with bladder cancer diagnosed after diagnosis of Wegener’s granulomatosis in a population based cohort of 1065 patients with Wegener’s granulomatosis in Sweden, 1969–94
Year of birth | Sex | Age at WG | Age at cancer | Time from WG to cancer (months) | Time from CY to cancer* (months) | Cumulative dose of CY (g) | Duration of CY (months) | Bladder cancer | Smoking status |
---|---|---|---|---|---|---|---|---|---|
WG, Wegener’s granulomatosis; CY, cyclophosphamide. | |||||||||
*Time from stopping CY treatment to appearance of bladder cancer; †this patient continued to receive cyclophosphamide even after the diagnosis of bladder cancer was made—that is, CY was never discontinued. | |||||||||
1913 | M | 73 | 77 | 57 | 0† | 108 | 86 | Non-invasive | Ex-smoker |
1915 | M | 58 | 66 | 96 | – | – | 96 | Non-invasive | No information |
1915 | M | 66 | 80 | 168 | 163 | 23 | 5 | Non-invasive | No information |
1910 | M | 75 | 83 | 103 | 101 | 115 | 98 | Invasive | Never smoker |
1922 | M | 68 | 73 | 70 | 14 | 178 | 56 | Invasive | Never smoker |
1926 | M | 55 | 63 | 98 | 0 | 234 | 98 | Non-invasive | Ex-smoker |
1933 | M | 41 | 56 | 180 | 2 | 224 | 178 | Invasive | Never smoker |
1933 | M | 47 | 62 | 180 | 67 | 140 | 53 | Non-invasive | Ex-smoker |
1900 | F | 74 | 78 | 48 | – | 0 | 0 | Invasive | Never smoker |
1909 | F | 70 | 74 | 51 | 1 | 54 | 50 | Non-invasive | No information |
1942 | F | 40 | 51 | 125 | 31 | 110 | 108 | Non-invasive | Never smoker |