Table 4

 Most common adverse events experienced during the 1 year study by treatment group

Adverse eventNDR 101 (n = 131)Diacerein (n = 85)Placebo (n = 85)p Value
The percentage of patients is shown.
Knee pain during or after IA injection249190.0088
Diarrhoea9418<0.0001
Nausea, vomiting4550.73
Gastralgia4850.43
Other gastrointestinal disorders91870.07
Respiratory system disorders (bronchitis, rhinitis…)1712160.48
Influenza-like symptoms3550.80
Skin disorders9810.06
Central and peripheral nervous disorders (headache, vertigo..)8520.16
Urine colouration0700.0009