Clinical and structural parameters observed at baseline and after five years’ follow up in patients primarily randomised to be treated with single or combined DMARDs during the first year
| Single therapy | Combination therapy | p Value | |
|---|---|---|---|
| Baseline DAS (mean (SD)) | 4.2 (0.7) | 4.2 (0.8) | 0.9 |
| Baseline HAQ (mean (SD)) | 1.4 (0.7) | 1.3 (0.8) | 0.5 |
| Baseline radiological score (median (25, 75% centiles)) | 0 (0, 3) | 0 (0, 3) | 0.7 |
| 5 Year DAS (mean (SD)) | 2.2 (1.1) | 2.2 (1) | 0.9 |
| 5 Year HAQ (mean (SD)) | 0.6 (0.6) | 0.6 (0.7) | 0.9 |
| 5 Year radiological score (median (25, 75% centiles)) | 8.5 (1.5, 17.2) | 7.5 (1.1, 27.3) | 0.7 |