Table 3

 Comparison of ASAS and BASDAI Scores before and after 12 weeks of treatment

Response measure: assessment pointPlacebo (n = 39)Etanercept (n = 45)p Value*
*Differences in mean percentage change, baseline to week 12, by the Cochrane-Mantel-Haenszel test.
ASAS, Assessments in Ankylosing Spondylitis; BASFI, Bath Ankylosing Spondylitis Functional Index; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index.
ASAS: Spinal inflammation
    Baseline (mean)62.967.5
    Week 12 (% change)52.6 (15.9)35.6 (43.3)0.003
ASAS: Nocturnal and total pain
    Baseline (mean)56.160.0
    Week 12 (% change)51.2 (6.2)31.0 (43.1)0.000
ASAS: Patient global assessment
    Baseline (mean)63.465.6
    Week 12 (% change)54.1 (12.6)38.4 (37.0)0.011
ASAS: Functional impairment (BASFI)
    Baseline (mean)57.260.2
    Week 12 (% change)53.9 (3.4)39.6 (35.4)0.000
BASDAI: Composite score
    Baseline (mean)58.661.0
    Week 12 (% change)50.1 (13.6)33.8 (43.6)0.001
BASDAI: Fatigue score
    Baseline (mean)59.068.2
    Week 12 (% change)54.8 (−4.9)38.4 (42.6)0.000