Table 2

Some angiogenesis inhibitors relevant to RA

Endogenous inhibitors:
    Cartilage derived factor: troponin-1
    IL4
    IL1Ra
    Angiostatin
    Endostatin
    2-Methoxyoestradiol
Exogenous inhibitors
    Angiostatic steroids
    Minocycline
    Fumigillin
    Chloroquine
    Sulfapyridine
    Methotrexate
    Gold compounds
    Penicillamine
    Thiol-containing compounds targeting macrophage derived angiogenic mediators
    Thalidomide
    TNFα inhibitors
    Taxol
    Cyclo-oxygenase-2 inhibitors