Table 1

Some angiogenesis inducers relevant to RA

Cytokines:
    Fibroblast growth factors such as FGF-2
    VEGF
    TGFβ
    TNFα
    Chemokines such as IL8, fractalkine
    IL18
    IL1
    Soluble adhesion molecules such as soluble E-selectin, soluble VCAM-1
    Glycoconjugates, such as the soluble 4A11 antigen
    Soluble CD 146
    The angiopoietin–Tie system