Articular damage to hands and feet in patients with RA with HLA-DMA*0103 phenotype in cohort 2
| Allele | Matched controls (n = 218) | Severe RA (n = 95) | Benign RA (n = 70) | OR (95% CI) | p |
|---|---|---|---|---|---|
| OR, odds ratio; CI, confidence interval. Disease severity was assessed using Larsen score on hand and foot radiographs. Severe RA corresponds to a Larsen score >3; benign RA corresponds to a Larsen score <2. χ2 test was used for analyses. | |||||
| Non DRB1*04 | |||||
| DMA*0103 + | 2 | 10 | 3 | ||
| DMA*0103 − | 120 | 28 | 45 | 5.4 (1.4 to 21.2) | 0.014 |
| DRB1*01/01and 01/X | |||||
| DMA*0103 + | 1 | 8 | 1 | ||
| DMA*0103 − | 43 | 16 | 11 | 11.8 (0.62 to 225) | 0.037 |