COBRA | Early arthritis clinic 1996–97 | Early arthritis clinic 2001 | Established disease active | Established disease remission | |
---|---|---|---|---|---|
Disease activity score (28 joints), at baseline ⩾5.1 is high and ⩽2.6 is remission. | |||||
Number | 134 | 26 | 21 | 56 | 56 |
Age, mean (SD) | 50 (12) | 62 (17) | 60 (14) | 60 (13) | 59 (14) |
No (%) male | 55 (41) | 9 (35) | 8 (38) | 9 (16) | 9 (16) |
Disease duration | Median 4 months (range 1.5–24) | 0 months | 0 months | 8 (9) years | 10 (9) years |
ESR | 55 (33) | 52 (28) | 43 (30) | 39 (22) | 15 (15) |
DAS28* | 5.9 (1.0) | 5.2 (0.8) | 5.8 (1.0) | 5.2 (1.5) | ⩽2.6 (0.7) |