Allele and genotype frequencies of ORα polymorphism in controls and SLE patients
| Control (n = 268) | SLE (n = 137) | Adult onset SLE (n = 96) | Childhood onset SLE (n = 41) | |
|---|---|---|---|---|
| *pc = 0.0174, OR = 1.79 (95% CI, 1.16 to 2.77) v control. | ||||
| †pc = 0.0045, OR = 0 (0 to 0.63) v control. | ||||
| ‡pc = 0.016, OR = 0 (0 to 0.71) v adult onset SLE. | ||||
| §pc = 0.0498, OR = 2.24 (1.09 to 4.64) v control. | ||||
| ¶p = 0.003, OR = 0.46 (0.27 to 0.80) v control. | ||||
| **p = 0.021, OR = 0.47 (0.25 to 0.90) v adult onset SLE. | ||||
| ††pc = 0.0255, OR = 0.42 (0.20 to 0.85) v control. | ||||
| CI, confidence interval; OR, odds ratio; SLE, systemic lupus erythematosus. | ||||
| For PvuII | ||||
| Allele P | 198 (36.9%) | 168 (61.3%) | 81 (42.2%) | 25 (30.5%) |
| p | 338 (63.1%) | 106 (38.7%) | 111 (57.8%) | 57 (69.5%) |
| Genotype PP | 44 (16.4%) | 15 (10.9%) | 15 (15.6%) | 0 (0%)†‡ |
| Pp | 110 (41.1%) | 76 (55.5%)* | 51 (53.1%) | 25 (61.0%)§ |
| pp | 114 (42.5%) | 46 (33.6%) | 30 (31.3%) | 16 (39.0%) |
| For XbaI | ||||
| Allele X | 90 (16.8%) | 58 (21.2%) | 33 (17.2%) | 25 (30.5%) |
| x | 446 (83.2%) | 216 (78.8%) | 159 (82.8%) | 57 (69.5%)¶** |
| Genotype XX | 14 (5.2%) | 10 (7.3%) | 5 (5.2%) | 5 (12.2%) |
| Xx | 62 (23.1%) | 38 (27.7%) | 23 (24.0%) | 15 (36.6%) |
| xx | 192 (71.7%) | 89 (65.0%) | 68 (70.8%) | 21 (51.2%)†† |